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#PALI — Palisade Bio Advances Phase 2 Ulcerative Colitis and Crohn's Disease Programs | ThinkSabio
Nov 13, 2026 · ThinkSabio Inc
Palisade Bio provided updates on its Phase 2 clinical programs, including its ulcerative colitis study and a separate Crohn's disease trial. The company reported continued enrollment progress and outlined expected timelines for upcoming clinical data.
🔹 Key Highlights
Phase 2 Ulcerative Colitis: The study is enrolling 204 patients across once-daily 15 mg and 30 mg doses, compared with placebo.
Topline Timeline: Results are expected in Q4 2027.
Site Activation: 29 of 30 planned U.S. sites have been activated, with approximately 115 sites planned globally.
Phase 2 Crohn's Disease: A separate 60-patient open-label study is progressing toward site activation before the end of 2026.
Crohn's Data: Topline results are expected in Q1 2028.
Potential Earlier Update: The company may provide an earlier update after a meaningful patient cohort completes 12 weeks of treatment, depending on enrollment progress.
💡 Why It Matters
Progress across both ulcerative colitis and Crohn's disease programs could expand Palisade Bio's opportunities in inflammatory bowel disease. Site activation and enrollment execution will be important near-term milestones. However, the programs remain clinical-stage, and the investment outlook depends on safety, efficacy, and future trial results.
Source: X — @dough
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