Top Downgrades:  AVTX: NEUTRAL @ Wainwright AVTX: NEUTRAL @ Guggenheim  CASS: MARKET PERFORM @ RJ CHMG: NEUTRAL @ Davidson DECK: UNDERWEIGHT @ Piper FR: OUTPERFORM @ RJ GL: NEUTRAL @ Piper NCLH: UNDERWEIGHT @ JPM NVR: UNDERPERFORM @ BAC ORI: OUTPERFORM @ RJ QGEN: NEUTRAL @ Baird  TMO: HOLD @ DZ Bank 23-OCT-2026 06:58 AM ET