PCVX ▼ -1.9% - Vaxcyte, Inc. $PCVX - Vaxcyte Appoints Chief Medical Officer and Chief Legal Officer; Narrows Guidance for Expected VAX-31 OPUS-1 Topline Data Vaxcyte shares fell 1.9% following the company's announcement that it has narrowed its guidance for when it expects topline data from its VAX-31 OPUS-1 trial. While the company also appointed new Chief Medical and Chief Legal Officers, the tighter timeline for trial results appears to have weighed on the stock, likely reflecting investor concerns about the narrowed window or revised expectations around the data readout. 03-SEP-2026 04:08 PM ET