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#NKTR — Nektar's Positive Phase 2b Results Support Phase 3 Program | ThinkSabio
Aug 25, 2026 · ThinkSabio Inc
Nektar Therapeutics (#NKTR) announced publication in The Lancet of positive Phase 2b REZOLVE-AD 16-week induction results for rezpegaldesleukin in moderate-to-severe atopic dermatitis.
🔹 Key Highlights
🧪 The study met all primary and key secondary endpoints.
📊 Results included EASI-75, EASI-90, Itch NRS, vIGA-AD, and BSA.
💊 The 24 µg/kg every-two-weeks (q2w) dose delivered the positive results.
🔬 The trial was a large, placebo-controlled study supporting T-reg modulation as a potential mechanism for chronic inflammatory disease.
🚀 Results support continued development in the Phase 3 ZENITH AD program.
💡 Why It Matters
The positive Phase 2b results strengthen the clinical case for rezpegaldesleukin and provide support for its continued advancement into Phase 3 development for atopic dermatitis.
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