SEC Filing Update: #SPRB Spruce Biosciences, Inc. : $52.64

Sector: Healthcare | YTD: 🔽 -41.80% The SEC disclosed Today (14-AUG-2026) that ORBIMED ADVISORS LLC has DECREASED #SPRB Shares by -33.90% 🔴 ADAR1 Capital Management, LLC also reported an increase in its holdings on the same day. * Previous Holdings: 200.00K Shares * Current Holdings: 132.20K Shares * Decrease -67.80K * Decreased (%)-33.90% * Ownership: 4.8% https://www.thinksabio.com/reports/isr/SPRB 📌 Institutional activity in the last 30 days for #SPRB: • INTEGRATED CORE STRATEGIES (US) – Increased holdings by 58,010 shares (04-AUG-2026) • ADAR1 Capital Management, LLC – Increased holdings by 9,117 shares (14-AUG-2026) • HIRSCHMAN ORIN – Newly bought 250,000 shares (27-JUL-2026) • BLACKROCK INC – Increased holdings by 170,898 shares (30-JUL-2026)